Version 5.4
Bos taurus Gene: KDM1B
Summary
InnateDB Gene IDBG-635853.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM1B
Gene Name Uncharacterized protein
Synonyms AOF1
Species Bos taurus
Ensembl Gene ENSBTAG00000014608
Encoded Proteins
IDBP-687746
lysine (K)-specific demethylase 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165097:
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:39166819-39204690
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019452 ENSBTAP00000019452
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific)
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006349 regulation of gene expression by genetic imprinting
GO:0034720 histone H3-K4 demethylation
GO:0043046 DNA methylation involved in gamete generation
GO:0044030 regulation of DNA methylation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000165097
View Gene Order
ENSMUSG00000038080
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_228178
HDMs demethylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_218274
Chromatin organization pathway
REACT_256030
HDMs demethylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BPZ5
UniProt Splice Variant
Entrez Gene 513667
UniGene Bt.62665
RefSeq XM_001254936 XM_002697549 XM_005196689 XM_005196690 XM_005196691 XM_005223819 XM_005223820 XM_005223821
HUGO HGNC:21577
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055618 DAAA02055619
GenPept
RNA Seq Atlas 513667

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca