InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KDM1B

Summary

InnateDB Protein

IDBP-687746.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KDM1B

Protein Name

lysine (K)-specific demethylase 1B

Synonyms

AOF1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000019452

InnateDB Gene

IDBG-635853 (KDM1B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016491	oxidoreductase activity
GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649	histone demethylase activity (H3-monomethyl-K4 specific)
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0006349	regulation of gene expression by genetic imprinting
GO:0034720	histone H3-K4 demethylation
GO:0043046	DNA methylation involved in gamete generation
GO:0044030	regulation of DNA methylation
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001327 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain
IPR002937 Amine oxidase
IPR002938 Monooxygenase, FAD-binding
IPR003953 FAD binding domain
IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like
IPR006076 FAD dependent oxidoreductase
IPR007526 SWIRM domain
IPR009057 Homeodomain-like
IPR011124 Zinc finger, CW-type
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM