Bos taurus Gene: MLLT4
Summary
InnateDB Gene IDBG-635948.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLLT4
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005557
Encoded Proteins
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130396:
This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:103847559-103927133
Strand Forward strand
Band
Transcripts
ENSBTAT00000007309 ENSBTAP00000007309
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005913 cell-cell adherens junction
GO:0030054 cell junction
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Cell-cell junction organization pathway
Adherens junctions interactions pathway
Cell junction organization pathway
Cell-Cell communication pathway
KEGG
Adherens junction pathway
Leukocyte transendothelial migration pathway
Tight junction pathway
Tight junction pathway
Adherens junction pathway
Leukocyte transendothelial migration pathway
INOH
PID NCI
E-cadherin signaling in the nascent adherens junction
Nectin adhesion pathway
SHP2 signaling
Stabilization and expansion of the E-cadherin adherens junction
PDGFR-beta signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.109811
RefSeq XM_002690394 XM_005199479 XM_005199480 XM_005199482 XM_005199483 XM_005211144 XM_005211145 XM_005211147 XM_005211148 XM_005211149 XM_581038
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas