Version 5.4
Bos taurus Gene: MYLIP
Summary
InnateDB Gene IDBG-636007.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYLIP
Gene Name E3 ubiquitin-protein ligase MYLIP
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004115
Encoded Proteins
IDBP-687892
myosin regulatory light chain interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000007944:
The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:40770315-40790973
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005377 ENSBTAP00000005377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006928 cellular component movement
GO:0007399 nervous system development
GO:0010989 negative regulation of low-density lipoprotein particle clearance
GO:0016567 protein ubiquitination
GO:0031648 protein destabilization
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process
GO:0042632 cholesterol homeostasis
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005622 intracellular
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000007944
View Gene Order
ENSMUSG00000038175
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.6814 Bt.73192
RefSeq NM_001102253 XM_005223783
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca