Version 5.4
Bos taurus Gene: SMOC2
Summary
InnateDB Gene IDBG-636035.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMOC2
Gene Name SPARC-related modular calcium-binding protein 2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013176
Encoded Proteins
IDBP-687929
SPARC-related modular calcium-binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112562:
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:104268693-104380527
Strand Forward strand
Band
Transcripts
ENSBTAT00000044700 ENSBTAP00000042177
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005539 glycosaminoglycan binding
GO:0008201 heparin binding
Biological Process
GO:0007165 signal transduction
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0005614 interstitial matrix
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000112562
View Gene Order
ENSMUSG00000023886
View Gene Order
Cross-References
SwissProt
TrEMBL F1N126
UniProt Splice Variant
Entrez Gene 615490
UniGene Bt.11271
RefSeq NM_001098134
HUGO HGNC:20323
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02027542 DAAA02027543
GenPept
RNA Seq Atlas 615490

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca