Version 5.4
Bos taurus Gene: CLIP3
Summary
InnateDB Gene IDBG-636080.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLIP3
Gene Name CAP-Gly domain-containing linker protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019674
Encoded Proteins
IDBP-688052
CAP-GLY domain containing linker protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105270:
This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:46877782-46890070
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026221 ENSBTAP00000026221
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0035594 ganglioside binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0010828 positive regulation of glucose transport
GO:0018230 peptidyl-L-cysteine S-palmitoylation
GO:0031115 negative regulation of microtubule polymerization
GO:0043065 positive regulation of apoptotic process
GO:0044091 membrane biogenesis
GO:0045444 fat cell differentiation
GO:0045807 positive regulation of endocytosis
GO:0072321 chaperone-mediated protein transport
GO:0090004 positive regulation of establishment of protein localization to plasma membrane
Cellular Component
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0031901 early endosome membrane
GO:0032588 trans-Golgi network membrane
GO:0045121 membrane raft
GO:0055038 recycling endosome membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105270
View Gene Order
ENSMUSG00000013921
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.56647
RefSeq NM_001205898
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca