Version 5.4
Bos taurus Gene: TRAP1
Summary
InnateDB Gene IDBG-636097.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRAP1
Gene Name Heat shock protein 75 kDa, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020109
Encoded Proteins
IDBP-688006
Heat shock protein 75 kDa, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126602:
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:2995416-3044580
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026786 ENSBTAP00000026786
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0006950 response to stress
GO:1901856 negative regulation of cellular respiration
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000126602
View Gene Order
ENSMUSG00000005981
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q2TBI4
TrEMBL M5FJZ9
UniProt Splice Variant
Entrez Gene 514472
UniGene Bt.58930
RefSeq NM_001038675 XM_005224437
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110148 GJ062847
GenPept AAI10149 DAA15580
RNA Seq Atlas 514472

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca