Version 5.4
Bos taurus Gene: RCVRN
Summary
InnateDB Gene IDBG-636121.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCVRN
Gene Name Recoverin
Synonyms RCV1
Species Bos taurus
Ensembl Gene ENSBTAG00000025088
Encoded Proteins
IDBP-688021
Recoverin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109047:
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:29653157-29661163
Strand Reverse strand
Band
Transcripts
ENSBTAT00000035069 ENSBTAP00000034949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0050896 response to stimulus
GO:0051924 regulation of calcium ion transport
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000109047
View Gene Order
ENSMUSG00000020907
View Gene Order
Pathways
NETPATH
REACTOME
REACT_205562
The phototransduction cascade pathway
REACT_223698
Visual phototransduction pathway
REACT_214353
Signal Transduction pathway
REACT_216038
Diseases associated with visual transduction pathway
REACT_207087
Disease pathway
REACT_209198
Inactivation, recovery and regulation of the phototransduction cascade pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_163722
The phototransduction cascade pathway
REACT_163919
Inactivation, recovery and regulation of the phototransduction cascade pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_188260
Visual phototransduction pathway
REACT_188266
Inactivation, recovery and regulation of the phototransduction cascade pathway
REACT_188265
The phototransduction cascade pathway
REACT_188257
Signal Transduction pathway
REACT_188255
Diseases associated with visual transduction pathway
KEGG
hsa04744
Phototransduction pathway
mmu04744
Phototransduction pathway
INOH
PID NCI
Cross-References
SwissProt P21457
TrEMBL
UniProt Splice Variant
Entrez Gene 281447
UniGene Bt.56904
RefSeq NM_174165
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL M95858 X63322
GenPept AAB59256 CAA44928
RNA Seq Atlas 281447

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca