InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RCVRN

Summary

InnateDB Protein

IDBP-688021.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RCVRN

Protein Name

Recoverin

Synonyms

RCV1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000034949

InnateDB Gene

IDBG-636121 (RCVRN)

Protein Structure

UniProt Annotation

Function

Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. {ECO:0000269PubMed:8392055}.

Subcellular Localization

Disease Associations

Tissue Specificity

Retina and pineal gland.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0007601	visual perception
GO:0007602	phototransduction
GO:0050896	response to stimulus
GO:0051924	regulation of calcium ion transport

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P21457

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

281447

UniGene

Bt.56904

RefSeq

NP_776590

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

M95858 X63322

GenPept

AAB59256 CAA44928