Version 5.4
| Bos taurus Gene: PRKCSH | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-636296.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PRKCSH | ||||||||
| Gene Name | phospholipase D1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000017490 | ||||||||
| Encoded Proteins |
phospholipase D1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075651:
This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:96517509-96676250 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
Role of phospholipids in phagocytosis pathway
Synthesis of PA pathway
Synthesis of PG pathway
Metabolism of lipids and lipoproteins pathway
Innate Immune System pathway
Glycerophospholipid biosynthesis pathway
Immune System pathway
Phospholipid metabolism pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Metabolism pathway
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| KEGG |
GnRH signaling pathway pathway
Glycerophospholipid metabolism pathway
Ether lipid metabolism pathway
Pancreatic cancer pathway
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
Pathways in cancer pathway
Glycerophospholipid metabolism pathway
Ether lipid metabolism pathway
GnRH signaling pathway pathway
Pancreatic cancer pathway
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
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| INOH | |||||||||
| PID NCI |
Alpha-synuclein signaling
IL8- and CXCR1-mediated signaling events
ErbB1 downstream signaling
CDC42 signaling events
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A6QR57 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514554 | ||||||||
| UniGene | Bt.17607 | ||||||||
| RefSeq | NM_001102001 XM_005201679 XM_005201682 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC150123 DAAA02002181 DAAA02002182 | ||||||||
| GenPept | AAI50124 | ||||||||
| RNA Seq Atlas | 514554 | ||||||||