Version 5.4
Bos taurus Gene: BT.22851
Summary
InnateDB Gene IDBG-636318.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.22851
Gene Name protein Muted homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000039732
Encoded Proteins
IDBP-688234
muted
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188428:
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:47244998-47269543
Strand Forward strand
Band
Transcripts
ENSBTAT00000025619 ENSBTAP00000025619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008089 anterograde axon cargo transport
GO:0016192 vesicle-mediated transport
GO:0032402 melanosome transport
GO:0032474 otolith morphogenesis
GO:0035646 endosome to melanosome transport
GO:0048066 developmental pigmentation
GO:0048490 anterograde synaptic vesicle transport
GO:0050942 positive regulation of pigment cell differentiation
Cellular Component
GO:0030133 transport vesicle
GO:0031083 BLOC-1 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000188428
View Gene Order
ENSMUSG00000038982
View Gene Order
Cross-References
SwissProt
TrEMBL F6R621
UniProt Splice Variant
Entrez Gene 505520
UniGene Bt.22851
RefSeq NM_001098875
HUGO HGNC:18561
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055800
GenPept
RNA Seq Atlas 505520
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca