Version 5.4
| Bos taurus Gene: PPP1R14A | |||||||
|---|---|---|---|---|---|---|---|
| Summary | |||||||
| InnateDB Gene | IDBG-636424.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | PPP1R14A | ||||||
| Gene Name | protein phosphatase 1 regulatory subunit 14A | ||||||
| Synonyms | |||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000023472 | ||||||
| Encoded Proteins |
protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
||||||
| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167641:
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011] |
||||||
| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 18:48282679-48286857 | ||||||
| Strand | Reverse strand | ||||||
| Band | |||||||
| Transcripts |
|
||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
|
||||||
| Gene Ontology | |||||||
Molecular Function |
|
||||||
| Biological Process |
|
||||||
| Cellular Component |
|
||||||
| Orthologs | |||||||
|
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH |
AndrogenReceptor pathway
|
||||||
| REACTOME | |||||||
| KEGG |
Vascular smooth muscle contraction pathway
Vascular smooth muscle contraction pathway
|
||||||
| INOH | |||||||
| PID NCI |
Integrin-linked kinase signaling
|
||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | E1BE60 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 615348 | ||||||
| UniGene | |||||||
| RefSeq | NM_001193070 | ||||||
| HUGO | |||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | DAAA02046993 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 615348 | ||||||