Bos taurus Gene: RGN
Summary
InnateDB Gene IDBG-636485.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGN
Gene Name Regucalcin
Synonyms GNL
Species Bos taurus
Ensembl Gene ENSBTAG00000046155
Encoded Proteins
Regucalcin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130988:
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:90732502-90747294
Strand Forward strand
Band
Transcripts
ENSBTAT00000065105 ENSBTAP00000055515
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004341 gluconolactonase activity
GO:0005509 calcium ion binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0030234 enzyme regulator activity
GO:0046872 metal ion binding
Biological Process
GO:0006874 cellular calcium ion homeostasis
GO:0019853 L-ascorbic acid biosynthetic process
GO:0032781 positive regulation of ATPase activity
GO:0050848 regulation of calcium-mediated signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pentose phosphate pathway pathway
Ascorbate and aldarate metabolism pathway
Pentose phosphate pathway pathway
Ascorbate and aldarate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9TTJ5
TrEMBL
UniProt Splice Variant
Entrez Gene 280910
UniGene Bt.502
RefSeq NM_173957 XM_005228064 XM_005228065 XM_005228066
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB035446 BC103461
GenPept AAI03462 BAA88080
RNA Seq Atlas 280910
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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