Version 5.4
Bos taurus Gene: MPV17
Summary
InnateDB Gene IDBG-636726.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPV17
Gene Name Protein Mpv17
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018269
Encoded Proteins
IDBP-688682
Protein Mpv17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115204:
This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:72315287-72324567
Strand Forward strand
Band
Transcripts
ENSBTAT00000024316 ENSBTAP00000024316
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.
Predicted by orthology
Total 45 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000002 mitochondrial genome maintenance
GO:0032836 glomerular basement membrane development
GO:0034614 cellular response to reactive oxygen species
GO:0042592 homeostatic process
GO:0048839 inner ear development
GO:0072593 reactive oxygen species metabolic process
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005777 peroxisome
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000115204
View Gene Order
ENSMUSG00000090262
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt Q2KIN6
TrEMBL
UniProt Splice Variant
Entrez Gene 505763
UniGene
RefSeq NM_001045929 XM_005212938
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112572
GenPept AAI12573
RNA Seq Atlas 505763

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca