Version 5.4
| Bos taurus Gene: EXOC2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-636829.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EXOC2 | ||||||||
| Gene Name | exocyst complex component 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000020215 | ||||||||
| Encoded Proteins |
exocyst complex component 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112685:
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 23:51917537-52015377 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Insulin processing pathway
Translocation of GLUT4 to the plasma membrane pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
Insulin processing pathway
Translocation of GLUT4 to the plasma membrane pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Arf6 trafficking events
Insulin Pathway
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BDW9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 513431 | ||||||||
| UniGene | Bt.47672 | ||||||||
| RefSeq | NM_001206159 XM_005223863 XM_005223864 | ||||||||
| HUGO | HGNC:24968 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02055935 DAAA02055936 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 513431 | ||||||||