Version 5.4
Bos taurus Gene: PREB
Summary
InnateDB Gene IDBG-636870.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PREB
Gene Name prolactin regulatory element-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007080
Encoded Proteins
IDBP-688844
prolactin regulatory element binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138073:
This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:72493261-72497358
Strand Forward strand
Band
Transcripts
ENSBTAT00000009307 ENSBTAP00000009307
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000138073
View Gene Order
ENSMUSG00000045302
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12507
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_22161
Post-translational protein modification pathway
REACT_11203
ER to Golgi Transport pathway
REACT_17015
Metabolism of proteins pathway
REACT_11123
Membrane Trafficking pathway
REACT_205304
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_209837
Membrane Trafficking pathway
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_203486
ER to Golgi Transport pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.12009
RefSeq NM_001076875
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca