Version 5.4
Mus musculus Gene: Preb
Summary
InnateDB Gene IDBG-146812.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Preb
Gene Name prolactin regulatory element binding
Synonyms C85705
Species Mus musculus
Ensembl Gene ENSMUSG00000045302
Encoded Proteins
IDBP-146814
prolactin regulatory element binding
IDBP-146816
prolactin regulatory element binding
IDBP-535927
prolactin regulatory element binding
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138073:
This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:30950853-30960330
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000074840 ENSMUSP00000074387
ENSMUST00000088063 ENSMUSP00000085379
ENSMUST00000148214 ENSMUSP00000120584
ENSMUST00000128093
ENSMUST00000155946
ENSMUST00000156351
ENSMUST00000135863
ENSMUST00000125524
ENSMUST00000125986
ENSMUST00000123211
ENSMUST00000142816
ENSMUST00000127081
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138073
View Gene Order
ENSBTAG00000007080
Not yet available
Pathways
NETPATH
REACTOME
REACT_205304
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_209837
Membrane Trafficking pathway
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_203486
ER to Golgi Transport pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12507
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_22161
Post-translational protein modification pathway
REACT_11203
ER to Golgi Transport pathway
REACT_17015
Metabolism of proteins pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.272414 Mm.445615
RefSeq NM_016703
OMIM
CCDS CCDS39051
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca