Bos taurus Gene: GSTT1
Summary
InnateDB Gene IDBG-637112.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GSTT1
Gene Name Glutathione S-transferase theta-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000040298
Encoded Proteins
Glutathione S-transferase theta-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:73300145-73307793
Strand Forward strand
Band
Transcripts
ENSBTAT00000007403 ENSBTAP00000007403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004364 glutathione transferase activity
GO:0005515 protein binding
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Glutathione conjugation pathway
Biological oxidations pathway
Metabolism pathway
Phase II conjugation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Phase II conjugation pathway
Metabolism pathway
Glutathione conjugation pathway
Biological oxidations pathway
KEGG
Glutathione metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q2NL00
TrEMBL
UniProt Splice Variant
Entrez Gene 517724
UniGene Bt.23204
RefSeq NM_001046232
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111289
GenPept AAI11290
RNA Seq Atlas 517724
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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