InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: S1PR3

Summary

InnateDB Gene

IDBG-637121.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S1PR3

Gene Name

sphingosine 1-phosphate receptor 3

Synonyms

EDG3

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011374

Encoded Proteins

IDBP-689104

sphingosine 1-phosphate receptor 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213694:
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:90649983-90663196

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015111

ENSBTAP00000015111

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005178	integrin binding
GO:0038036	sphingosine-1-phosphate receptor activity

Biological Process

GO:0001816	cytokine production
GO:0003376	sphingosine-1-phosphate signaling pathway
GO:0006954	inflammatory response
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0032651	regulation of interleukin-1 beta production
GO:1903141	negative regulation of establishment of endothelial barrier