Version 5.4
Bos taurus Gene: ASXL2
Summary
InnateDB Gene IDBG-637157.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASXL2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019983
Encoded Proteins
IDBP-689145
additional sex combs like 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143970:
ASXL2 is a human homolog of the Drosophila asx gene. Drosophila asx is an enhancer of trithorax (see MIM 159555) and polycomb (see MIM 610231) (ETP) gene that encodes a chromatin protein with dual functions in transcriptional activation and silencing (Katoh and Katoh, 2003 [PubMed 12888926]).[supplied by OMIM, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:73602730-73638589
Strand Forward strand
Band
Transcripts
ENSBTAT00000026618 ENSBTAP00000026618
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0042975 peroxisome proliferator activated receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007507 heart development
GO:0007512 adult heart development
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0045600 positive regulation of fat cell differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048704 embryonic skeletal system morphogenesis
GO:1900159 positive regulation of bone mineralization involved in bone maturation
GO:1902466 positive regulation of histone H3-K27 trimethylation
Cellular Component
GO:0000790 nuclear chromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143970
View Gene Order
ENSMUSG00000037486
View Gene Order
Cross-References
SwissProt
TrEMBL F1N2W4
UniProt Splice Variant
Entrez Gene 100140419
UniGene Bt.33270
RefSeq XM_001787633 XM_002691461 XM_005193938 XM_005193939 XM_005193940 XM_005213080 XM_005213081 XM_005213082
HUGO HGNC:23805
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031617
GenPept
RNA Seq Atlas 100140419

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca