Version 5.4
Bos taurus Gene: YME1L1
Summary
InnateDB Gene IDBG-637158.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YME1L1
Gene Name ATP-dependent zinc metalloprotease YME1L1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016445
Encoded Proteins
IDBP-689147
ATP-dependent metalloprotease YME1L1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136758:
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:17986323-18015111
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021868 ENSBTAP00000021868
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006508 proteolysis
GO:0006515 misfolded or incompletely synthesized protein catabolic process
GO:0007005 mitochondrion organization
GO:0008283 cell proliferation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000136758
View Gene Order
ENSMUSG00000026775
View Gene Order
Cross-References
SwissProt
TrEMBL A6QR12
UniProt Splice Variant
Entrez Gene 505118
UniGene Bt.1786
RefSeq NM_001101850 XM_005214173
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC150071 DAAA02035354
GenPept AAI50072
RNA Seq Atlas 505118

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca