Bos taurus Gene: KCNAB1
Summary
InnateDB Gene IDBG-637312.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNAB1
Gene Name Voltage-gated potassium channel subunit beta-1
Synonyms Kvbeta1.1
Species Bos taurus
Ensembl Gene ENSBTAG00000018465
Encoded Proteins
Voltage-gated potassium channel subunit beta-1
Voltage-gated potassium channel subunit beta-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169282:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:112013084-112455492
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024576 ENSBTAP00000024576
ENSBTAT00000065699 ENSBTAP00000054768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007611 learning or memory
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:1901016 regulation of potassium ion transmembrane transporter activity
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Neuronal System pathway
Voltage gated Potassium channels pathway
Potassium Channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Voltage gated Potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
Potassium Channels pathway
Neuronal System pathway
Voltage gated Potassium channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.47454
RefSeq NM_001025336
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas