Bos taurus Gene: BT.55996 | |||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||
InnateDB Gene | IDBG-637317.3 | ||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||
Gene Symbol | BT.55996 | ||||||||||||||||||||||||||||
Gene Name | nuclear receptor coactivator 1 | ||||||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000015007 | ||||||||||||||||||||||||||||
Encoded Proteins |
Uncharacterized protein
Uncharacterized protein
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Protein Structure | |||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000084676:
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||
Genomic Location | Chromosome 11:74511607-74590933 | ||||||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||||||
Band | |||||||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 87 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||
NETPATH |
AndrogenReceptor pathway
TGF_beta_Receptor pathway
IL6 pathway
Leptin pathway
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REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Recycling of bile acids and salts pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Endogenous sterols pathway
RORA activates circadian gene expression pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
REV-ERBA represses gene expression pathway
Circadian Clock pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
Transcriptional regulation of white adipocyte differentiation pathway
Transmembrane transport of small molecules pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Mitochondrial biogenesis pathway
Cytochrome P450 - arranged by substrate type pathway
Orphan transporters pathway
Transcriptional activation of mitochondrial biogenesis pathway
Metabolism pathway
Biological oxidations pathway
Gene Expression pathway
Phase 1 - Functionalization of compounds pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
Rora activates circadian gene expression pathway
Circadian Clock pathway
Cytochrome P450 - arranged by substrate type pathway
Transcriptional regulation of white adipocyte differentiation pathway
Organelle biogenesis and maintenance pathway
Mus musculus biological processes pathway
Phase 1 - Functionalization of compounds pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Circadian Clock pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Recycling of bile acids and salts pathway
REV-ERBA represses gene expression pathway
RORA activates circadian gene expression pathway
Orphan transporters pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Endogenous sterols pathway
Synthesis of bile acids and bile salts pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Transcriptional activation of mitochondrial biogenesis pathway
Transmembrane transport of small molecules pathway
Gene Expression pathway
PPARA activates gene expression pathway
Developmental Biology pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Biological oxidations pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Generic Transcription Pathway pathway
Mitochondrial biogenesis pathway
Bile acid and bile salt metabolism pathway
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KEGG | |||||||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||||||
PID NCI |
RXR and RAR heterodimerization with other nuclear receptor
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Notch-mediated HES/HEY network
Glucocorticoid receptor regulatory network
Retinoic acid receptors-mediated signaling
Regulation of nuclear SMAD2/3 signaling
HIF-1-alpha transcription factor network
Regulation of Androgen receptor activity
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Cross-References | |||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
UniGene | Bt.55996 | ||||||||||||||||||||||||||||
RefSeq | NM_001206215 XM_005212984 XM_005212985 XM_005212986 XM_005212987 XM_005212988 | ||||||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||||||