Bos taurus Gene: MYBPC3 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-637371.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | MYBPC3 | ||||||||||||||||
Gene Name | myosin-binding protein C, cardiac-type | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000021707 | ||||||||||||||||
Encoded Proteins |
myosin-binding protein C, cardiac-type
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134571:
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 15:78383688-78401416 | ||||||||||||||||
Strand | Reverse strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Striated Muscle Contraction pathway
Muscle contraction pathway
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KEGG |
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | Q0VD56 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 767614 | ||||||||||||||||
UniGene | Bt.64787 | ||||||||||||||||
RefSeq | NM_001076536 XM_005216510 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | BC119825 DAAA02041602 | ||||||||||||||||
GenPept | AAI19826 | ||||||||||||||||
RNA Seq Atlas | 767614 | ||||||||||||||||