InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TRPV2

Summary

InnateDB Gene

IDBG-637422.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRPV2

Gene Name

transient receptor potential cation channel subfamily V member 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000003014

Encoded Proteins

IDBP-689441

transient receptor potential cation channel subfamily V member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

InnateDB Annotation from Orthologs

Summary

PMID 20118928

[Homo sapiens] TRPV2 has fundamental importance in innate immunity by participating in macrophage particle binding and early phagocytosis.

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187688:
This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:33816540-33834542

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000003922

ENSBTAP00000003922

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005261	cation channel activity
GO:0005262	calcium channel activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0009266	response to temperature stimulus
GO:0009408	response to heat
GO:0045773	positive regulation of axon extension
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport
GO:0090280	positive regulation of calcium ion import

Cellular Component

GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0032584	growth cone membrane
GO:0044295	axonal growth cone
GO:0044297	cell body