Bos taurus Gene: PIGL
Summary
InnateDB Gene IDBG-637455.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGL
Gene Name N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013273
Encoded Proteins
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108474:
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:33888404-33930428
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017653 ENSBTAP00000017653
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt A6QQ24
TrEMBL
UniProt Splice Variant
Entrez Gene 507080
UniGene Bt.59643
RefSeq NM_001100311
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149604
GenPept AAI49605
RNA Seq Atlas 507080