Version 5.4
| Bos taurus Gene: ARHGEF26 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-637491.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ARHGEF26 | ||||||||
| Gene Name | Src homology 3 domain-containing guanine nucleotide exchange factor | ||||||||
| Synonyms | SGEF | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000013439 | ||||||||
| Encoded Proteins |
Rho guanine nucleotide exchange factor (GEF) 26
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114790:
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:114292426-114431455 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Bacterial invasion of epithelial cells pathway
Bacterial invasion of epithelial cells pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1B7M1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 531741 | ||||||||
| UniGene | Bt.91380 | ||||||||
| RefSeq | NM_001205989 XM_005201797 | ||||||||
| HUGO | HGNC:24490 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02002574 DAAA02002575 DAAA02002576 DAAA02002577 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 531741 | ||||||||