Bos taurus Gene: ACCN3
Summary
InnateDB Gene IDBG-637518.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACCN3
Gene Name amiloride-sensitive cation channel 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007762
Encoded Proteins
amiloride-sensitive cation channel 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213199:
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:114424078-114428038
Strand Forward strand
Band
Transcripts
ENSBTAT00000010209 ENSBTAP00000010209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005272 sodium channel activity
GO:0015280 ligand-gated sodium channel activity
GO:0042931 enterobactin transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0009408 response to heat
GO:0009612 response to mechanical stimulus
GO:0010447 response to acidity
GO:0034220 ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0042930 enterobactin transport
GO:0050907 detection of chemical stimulus involved in sensory perception
GO:0050915 sensory perception of sour taste
GO:0050961 detection of temperature stimulus involved in sensory perception
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0050968 detection of chemical stimulus involved in sensory perception of pain
GO:0050974 detection of mechanical stimulus involved in sensory perception
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Stimuli-sensing channels pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.24773
RefSeq NM_001191251
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas