InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DLL3

Summary

InnateDB Gene

IDBG-637637.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DLL3

Gene Name

delta-like protein 3 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000010483

Encoded Proteins

IDBP-689662

delta-like 3 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090932:
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:49443971-49451079

Strand

Forward strand

Band

Transcripts

ENSBTAT00000013852

ENSBTAP00000013852

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001501	skeletal system development
GO:0001756	somitogenesis
GO:0007219	Notch signaling pathway
GO:0007275	multicellular organismal development
GO:0007386	compartment pattern specification
GO:0009888	tissue development
GO:0048339	paraxial mesoderm development
GO:0050768	negative regulation of neurogenesis