Version 5.4
Bos taurus Gene: CPB1
Summary
InnateDB Gene IDBG-637896.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPB1
Gene Name Carboxypeptidase B
Synonyms pCPB
Species Bos taurus
Ensembl Gene ENSBTAG00000000456
Encoded Proteins
IDBP-689942
Carboxypeptidase B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153002:
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:120278804-120315813
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000580 ENSBTAP00000000580
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000153002
View Gene Order
ENSMUSG00000011463
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_147707
Metabolism of Angiotensinogen to Angiotensins pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
KEGG
hsa04972
Pancreatic secretion pathway
hsa04974
Protein digestion and absorption pathway
mmu04974
Protein digestion and absorption pathway
mmu04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt P00732
TrEMBL B1PZ69
UniProt Splice Variant
Entrez Gene 510039
UniGene Bt.28370
RefSeq NM_001105350
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL EU515132
GenPept ACA96505
RNA Seq Atlas 510039

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca