Bos taurus Gene: USP9X
Summary
InnateDB Gene IDBG-637955.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP9X
Gene Name ubiquitin specific protease 9, Y-linked
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006242
Encoded Proteins
ubiquitin specific protease 9, Y-linked
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124486:
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:107783133-107862518
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050390 ENSBTAP00000047095
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 90 interaction(s) predicted by orthology.
Predicted by orthology
Total 90 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0016787 hydrolase activity
GO:0036459 ubiquitinyl hydrolase activity
GO:0070410 co-SMAD binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001764 neuron migration
GO:0006508 proteolysis
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0009791 post-embryonic development
GO:0016579 protein deubiquitination
GO:0021698 cerebellar cortex structural organization
GO:0021766 hippocampus development
GO:0030509 BMP signaling pathway
GO:0048675 axon extension
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1990138 neuron projection extension
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0030426 growth cone
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway
Generic Transcription Pathway pathway
SMAD4 MH2 Domain Mutants in Cancer pathway
Loss of Function of SMAD4 in Cancer pathway
Loss of Function of SMAD2/3 in Cancer pathway
Signaling by TGF-beta Receptor Complex in Cancer pathway
TGFBR2 MSI Frameshift Mutants in Cancer pathway
Signal Transduction pathway
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer pathway
SMAD2/3 MH2 Domain Mutants in Cancer pathway
Loss of Function of TGFBR2 in Cancer pathway
SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway
TGFBR1 KD Mutants in Cancer pathway
Loss of Function of TGFBR1 in Cancer pathway
TGFBR1 LBD Mutants in Cancer pathway
TGFBR2 Kinase Domain Mutants in Cancer pathway
Gene Expression pathway
Disease pathway
Signaling by TGF-beta Receptor Complex pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.109855 Bt.109882 Bt.110558 Bt.110666 Bt.110829
RefSeq XM_001787392 XM_002700206 XM_002700207 XM_003584688 XM_005200483
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas