Version 5.4
Bos taurus Gene: SORBS1
Summary
InnateDB Gene IDBG-637958.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SORBS1
Gene Name sorbin and SH3 domain-containing protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002880
Encoded Proteins
IDBP-689996
sorbin and SH3 domain-containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095637:
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:16721039-16919269
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003743 ENSBTAP00000003743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007015 actin filament organization
GO:0008286 insulin receptor signaling pathway
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000095637
View Gene Order
ENSMUSG00000025006
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20558
Smooth Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
hsa04520
Adherens junction pathway
hsa04910
Insulin signaling pathway pathway
hsa03320
PPAR signaling pathway pathway
mmu04910
Insulin signaling pathway pathway
mmu03320
PPAR signaling pathway pathway
mmu04520
Adherens junction pathway
INOH
PID NCI
insulin_pathway
Insulin Pathway
Cross-References
SwissProt
TrEMBL Q0VCF1
UniProt Splice Variant
Entrez Gene 504625
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120200 DAAA02058874 DAAA02058875 DAAA02058876 DAAA02058877 DAAA02058878 DAAA02058879 DAAA02058880 DAAA02058881
GenPept AAI20201
RNA Seq Atlas 504625

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca