Version 5.4
Bos taurus Gene: GNB1L
Summary
InnateDB Gene IDBG-638137.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNB1L
Gene Name guanine nucleotide-binding protein subunit beta-like protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021052
Encoded Proteins
IDBP-690192
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185838:
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:74852397-74880531
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029367 ENSBTAP00000029367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035176 social behavior
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000185838
View Gene Order
ENSMUSG00000000884
View Gene Order
Cross-References
SwissProt
TrEMBL F1MBU4
UniProt Splice Variant
Entrez Gene 513071
UniGene Bt.62225
RefSeq NM_001192340
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045774 DAAA02045775 DAAA02045776
GenPept
RNA Seq Atlas 513071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca