Version 5.4
Bos taurus Gene: COPS3
Summary
InnateDB Gene IDBG-638317.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPS3
Gene Name COP9 signalosome complex subunit 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018973
Encoded Proteins
IDBP-690390
COP9 signalosome complex subunit 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141030:
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35490628-35508807
Strand Forward strand
Band
Transcripts
ENSBTAT00000025255 ENSBTAP00000025255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.
Predicted by orthology
Total 59 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0010388 cullin deneddylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008180 COP9 signalosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000141030
View Gene Order
ENSMUSG00000019373
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt A6H7B5
TrEMBL
UniProt Splice Variant
Entrez Gene 507932
UniGene Bt.3232
RefSeq NM_001098904
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146183
GenPept AAI46184
RNA Seq Atlas 507932

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca