Version 5.4
| Bos taurus Gene: RASA2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-638339.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RASA2 | ||||||||
| Gene Name | ras GTPase-activating protein 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000015413 | ||||||||
| Encoded Proteins |
RAS p21 protein activator 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155903:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:128345232-128468029 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
MAPK signaling pathway pathway
MAPK signaling pathway pathway
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| INOH | |||||||||
| PID NCI |
Regulation of Ras family activation
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1N795 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 533491 | ||||||||
| UniGene | Bt.106403 Bt.21170 | ||||||||
| RefSeq | NM_001193020 XM_005201878 | ||||||||
| HUGO | HGNC:9872 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02002889 DAAA02002890 DAAA02002891 DAAA02002892 DAAA02002893 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 533491 | ||||||||