Version 5.4
Bos taurus Gene: RGS3
Summary
InnateDB Gene IDBG-638369.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS3
Gene Name regulator of G-protein signaling 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004499
Encoded Proteins
IDBP-690488
regulator of G-protein signaling 3
IDBP-690493
regulator of G-protein signaling 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138835:
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:104422822-104543026
Strand Forward strand
Band
Transcripts
ENSBTAT00000061169 ENSBTAP00000053205
ENSBTAT00000005904 ENSBTAP00000005904
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0038032 termination of G-protein coupled receptor signaling pathway
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000138835
View Gene Order
ENSMUSG00000059810
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
INOH website
GPCR signaling pathway
INOH website
GPCR signaling pathway
PID NCI
ephrinbrevpathway
Ephrin B reverse signaling
Cross-References
SwissProt
TrEMBL F1MM15
UniProt Splice Variant
Entrez Gene 527349
UniGene
RefSeq XM_005210523 XM_005210525 XM_005210529 XM_005210531 XM_005210532 NM_001077973 XM_005210524
HUGO HGNC:9999
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02024571 DAAA02024572 DAAA02024573 DAAA02024574
GenPept
RNA Seq Atlas 527349

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca