Version 5.4
Bos taurus Gene: USP22
Summary
InnateDB Gene IDBG-638380.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP22
Gene Name Ubiquitin carboxyl-terminal hydrolase 22
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008978
Encoded Proteins
IDBP-690442
Ubiquitin carboxyl-terminal hydrolase 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124422:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35728070-35746498
Strand Reverse strand
Band
Transcripts
ENSBTAT00000011818 ENSBTAP00000011818
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0008270 zinc ion binding
GO:0010485 H4 histone acetyltransferase activity
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0036459 ubiquitinyl hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006508 proteolysis
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007049 cell cycle
GO:0016568 chromatin modification
GO:0016574 histone ubiquitination
GO:0016578 histone deubiquitination
GO:0016579 protein deubiquitination
GO:0043967 histone H4 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045931 positive regulation of mitotic cell cycle
Cellular Component
GO:0000124 SAGA complex
GO:0005634 nucleus
GO:0070461 SAGA-type complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124422
View Gene Order
ENSMUSG00000042506
View Gene Order
Pathways
NETPATH
REACTOME
REACT_207632
Chromatin organization pathway
REACT_219482
HATs acetylate histones pathway
REACT_227044
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_218274
Chromatin organization pathway
REACT_226917
HATs acetylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P0C8Z3
TrEMBL
UniProt Splice Variant
Entrez Gene 509694
UniGene Bt.12486
RefSeq NM_001166567
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL EE333442 EH202007 EV691513
GenPept
RNA Seq Atlas 509694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca