Version 5.4
Homo sapiens Gene: USP22
Summary
InnateDB Gene IDBG-35418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP22
Gene Name ubiquitin specific peptidase 22
Synonyms USP3L
Species Homo sapiens
Ensembl Gene ENSG00000124422
Encoded Proteins
IDBP-35420
ubiquitin specific peptidase 22
IDBP-764420
IDBP-584538
ubiquitin specific peptidase 22
IDBP-760263
IDBP-764098
IDBP-762341
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:20999593-21043760
Strand Reverse strand
Band p11.2
Transcripts
ENST00000261497 ENSP00000261497
ENST00000455117
ENST00000463692
ENST00000478443
ENST00000476111 ENSP00000468457
ENST00000537526 ENSP00000440950
ENST00000579645 ENSP00000464398
ENST00000577610
ENST00000582335 ENSP00000464499
ENST00000584538 ENSP00000468748
ENST00000578446
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
Experimentally validated
Total 51 [view]
Protein-Protein 51 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0010485 H4 histone acetyltransferase activity
GO:0019899 enzyme binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007049 cell cycle
GO:0009790 embryo development
GO:0016574 histone ubiquitination
GO:0016578 histone deubiquitination
GO:0016579 protein deubiquitination
GO:0043967 histone H4 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045931 positive regulation of mitotic cell cycle
Cellular Component
GO:0000124 SAGA complex
GO:0070461 SAGA-type complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042506
View Gene Order
ENSBTAG00000008978
Not yet available
Pathways
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.462492
RefSeq NM_015276 XM_005256575
HUGO
OMIM
CCDS CCDS42285
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca