Bos taurus Gene: LAMB3 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-638390.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | LAMB3 | ||||||
Gene Name | laminin subunit beta-3 precursor | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000016542 | ||||||
Encoded Proteins |
laminin subunit beta-3
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196878:
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 16:75567714-75610920 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH |
Alpha6Beta4Integrin pathway
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REACTOME |
Anchoring fibril formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Type I hemidesmosome assembly pathway
Cell-Cell communication pathway
Extracellular matrix organization pathway
Cell junction organization pathway
Degradation of the extracellular matrix pathway
Non-integrin membrane-ECM interactions pathway
Laminin interactions pathway
Collagen formation pathway
Collagen formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Type I hemidesmosome assembly pathway
Anchoring fibril formation pathway
Extracellular matrix organization pathway
Laminin interactions pathway
Cell junction organization pathway
Cell-Cell communication pathway
Degradation of the extracellular matrix pathway
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KEGG |
ECM-receptor interaction pathway
Small cell lung cancer pathway
Focal adhesion pathway
Pathways in cancer pathway
Amoebiasis pathway
Toxoplasmosis pathway
ECM-receptor interaction pathway
Small cell lung cancer pathway
Focal adhesion pathway
Pathways in cancer pathway
Amoebiasis pathway
Toxoplasmosis pathway
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INOH |
Integrin signaling pathway pathway
Integrin signaling pathway pathway
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PID NCI |
Beta1 integrin cell surface interactions
Alpha6 beta4 integrin-ligand interactions
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | F1MMK1 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 529939 | ||||||
UniGene | Bt.16740 | ||||||
RefSeq | NM_001081596 XM_005217367 XM_005217368 | ||||||
HUGO | HGNC:6490 | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02043815 DAAA02043816 | ||||||
GenPept | |||||||
RNA Seq Atlas | 529939 | ||||||