Version 5.4
Bos taurus Gene: PI4K2A
Summary
InnateDB Gene IDBG-638447.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PI4K2A
Gene Name phosphatidylinositol 4-kinase type 2-alpha
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002010
Encoded Proteins
IDBP-690519
phosphatidylinositol 4-kinase type 2-alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155252:
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:18684202-18710907
Strand Forward strand
Band
Transcripts
ENSBTAT00000002604 ENSBTAP00000002604
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0030425 dendrite
GO:0042734 presynaptic membrane
GO:0043025 neuronal cell body
GO:0044231 host cell presynaptic membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000155252
View Gene Order
ENSMUSG00000025178
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_8
Wnt pathway
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_120756
Synthesis of PIPs at the early endosome membrane pathway
REACT_120836
Synthesis of PIPs at the Golgi membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
REACT_198975
Synthesis of PIPs at the early endosome membrane pathway
REACT_198973
Synthesis of PIPs at the plasma membrane pathway
REACT_198970
Synthesis of PIPs at the Golgi membrane pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
wnt_canonical_pathway
Canonical Wnt signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.6575
RefSeq NM_001100316
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca