Bos taurus Gene: IPO8
Summary
InnateDB Gene IDBG-638507.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IPO8
Gene Name importin-8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014106
Encoded Proteins
importin 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133704:
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:79274076-79339563
Strand Forward strand
Band
Transcripts
ENSBTAT00000018760 ENSBTAP00000018760
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transcriptional regulation by small RNAs pathway
Gene Expression pathway
Regulatory RNA pathways pathway
Transcriptional regulation by small RNAs pathway
Gene Expression pathway
Regulatory RNA pathways pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B8Q9
UniProt Splice Variant
Entrez Gene 523408
UniGene Bt.32543
RefSeq NM_001206120 XM_005198373
HUGO HGNC:9853
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013940 DAAA02013941
GenPept
RNA Seq Atlas 101910123 523408