InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CACNA1G

Summary

InnateDB Gene

IDBG-638512.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CACNA1G

Gene Name

voltage-dependent T-type calcium channel subunit alpha-1G

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009835

Encoded Proteins

IDBP-690590

calcium channel, voltage-dependent, T type, alpha 1G subunit

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006283:
Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:36731340-36792932

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000012985

ENSBTAP00000012985

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005245	voltage-gated calcium channel activity
GO:0005262	calcium channel activity
GO:0005515	protein binding
GO:0008332	low voltage-gated calcium channel activity
GO:0097110	scaffold protein binding

Biological Process

GO:0001508	action potential
GO:0002027	regulation of heart rate
GO:0006810	transport
GO:0006811	ion transport
GO:0006816	calcium ion transport
GO:0007268	synaptic transmission
GO:0010045	response to nickel cation
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0055085	transmembrane transport
GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
GO:0070509	calcium ion import
GO:0070588	calcium ion transmembrane transport
GO:0086010	membrane depolarization during action potential