InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PGM1

Summary

InnateDB Gene

IDBG-638534.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PGM1

Gene Name

Phosphoglucomutase-1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019011

Encoded Proteins

IDBP-690613

Phosphoglucomutase-1

IDBP-690615

Phosphoglucomutase-1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079739:
The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]
The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90%% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:82250292-82315999

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000043425	ENSBTAP00000040998
ENSBTAT00000025308	ENSBTAP00000025308

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004614	phosphoglucomutase activity
GO:0016853	isomerase activity
GO:0016868	intramolecular transferase activity, phosphotransferases
GO:0046872	metal ion binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0005978	glycogen biosynthetic process
GO:0006006	glucose metabolic process
GO:0019388	galactose catabolic process