Version 5.4
Bos taurus Gene: LHX6
Summary
InnateDB Gene IDBG-638551.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LHX6
Gene Name LIM/homeobox protein Lhx6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005525
Encoded Proteins
IDBP-690621
LIM homeobox 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106852:
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:93069014-93090242
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007266 ENSBTAP00000007266
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021800 cerebral cortex tangential migration
GO:0021853 cerebral cortex GABAergic interneuron migration
GO:0021877 forebrain neuron fate commitment
GO:0021884 forebrain neuron development
GO:0021895 cerebral cortex neuron differentiation
GO:0048469 cell maturation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000106852
View Gene Order
ENSMUSG00000026890
View Gene Order
Cross-References
SwissProt
TrEMBL E1B8I6
UniProt Splice Variant
Entrez Gene 541261
UniGene Bt.32055 Bt.83459
RefSeq NM_001192848 XM_005213033
HUGO HGNC:21735
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02032024 DAAA02032025
GenPept
RNA Seq Atlas 541261

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca