Bos taurus Gene: BT.66624
Summary
InnateDB Gene IDBG-638725.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.66624
Gene Name inositol 1,4,5-trisphosphate receptor type 2
Synonyms insP3R2
Species Bos taurus
Ensembl Gene ENSBTAG00000002313
Encoded Proteins
inositol 1,4,5-trisphosphate receptor type 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123104:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:83398954-83986176
Strand Forward strand
Band
Transcripts
ENSBTAT00000002982 ENSBTAP00000002982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262 calcium channel activity
GO:0005488 binding
GO:0015278 calcium-release channel activity
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0001666 response to hypoxia
GO:0006810 transport
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071320 cellular response to cAMP
GO:0071361 cellular response to ethanol
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
GO:0033017 sarcoplasmic reticulum membrane
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
BCR pathway
REACTOME
DAG and IP3 signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
Role of phospholipids in phagocytosis pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
Elevation of cytosolic Ca2+ levels pathway
Platelet homeostasis pathway
Effects of PIP2 hydrolysis pathway
PLC-gamma1 signalling pathway
EGFR interacts with phospholipase C-gamma pathway
Signaling by EGFR pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
PLC beta mediated events pathway
Opioid Signalling pathway
PLCG1 events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Phospholipase C-mediated cascade pathway
Signaling by FGFR pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Signaling by FGFR in disease pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Platelet calcium homeostasis pathway
Signaling by VEGF pathway
Signaling by GPCR pathway
Innate Immune System pathway
Platelet activation, signaling and aggregation pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G-protein mediated events pathway
Adaptive Immune System pathway
Immune System pathway
VEGFR2 mediated cell proliferation pathway
VEGFA-VEGFR2 Pathway pathway
NGF signalling via TRKA from the plasma membrane pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Metabolism pathway
FCERI mediated Ca+2 mobilization pathway
Signaling by the B Cell Receptor (BCR) pathway
Disease pathway
Hemostasis pathway
Innate Immune System pathway
Signaling by the B Cell Receptor (BCR) pathway
Signaling by ERBB2 pathway
PLCG1 events in ERBB2 signaling pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
GPCR downstream signaling pathway
Disease pathway
Platelet homeostasis pathway
Hemostasis pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
Integration of energy metabolism pathway
Role of phospholipids in phagocytosis pathway
Signaling by VEGF pathway
Platelet calcium homeostasis pathway
Signaling by FGFR in disease pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
beta-catenin independent WNT signaling pathway
VEGFR2 mediated cell proliferation pathway
PLC-gamma1 signalling pathway
Metabolism pathway
Immune System pathway
Platelet activation, signaling and aggregation pathway
EGFR interacts with phospholipase C-gamma pathway
Regulation of insulin secretion pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
Effects of PIP2 hydrolysis pathway
Signaling by EGFR pathway
Phospholipase C-mediated cascade pathway
VEGFA-VEGFR2 Pathway pathway
Fc epsilon receptor (FCERI) signaling pathway
Ca2+ pathway pathway
FCERI mediated Ca+2 mobilization pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Signaling by PDGF pathway
DAG and IP3 signaling pathway
Elevation of cytosolic Ca2+ levels pathway
NGF signalling via TRKA from the plasma membrane pathway
G alpha (q) signalling events pathway
Opioid Signalling pathway
Signal Transduction pathway
Signaling by FGFR pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
PLC beta mediated events pathway
G-protein mediated events pathway
Signaling by EGFR in Cancer pathway
DAP12 interactions pathway
DAP12 signaling pathway
KEGG
GnRH signaling pathway pathway
Gap junction pathway
Long-term potentiation pathway
Alzheimer's disease pathway
Phosphatidylinositol signaling system pathway
Long-term depression pathway
Calcium signaling pathway pathway
Vascular smooth muscle contraction pathway
Oocyte meiosis pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Salivary secretion pathway
Calcium signaling pathway pathway
Alzheimer's disease pathway
Gap junction pathway
Phosphatidylinositol signaling system pathway
GnRH signaling pathway pathway
Long-term potentiation pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
Oocyte meiosis pathway
Gastric acid secretion pathway
Salivary secretion pathway
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.9026
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas