Version 5.4
Bos taurus Gene: COLEC11
Summary
InnateDB Gene IDBG-638985.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COLEC11
Gene Name Collectin-11
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016225
Encoded Proteins
IDBP-691100
Collectin-11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118004:
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:112869671-112892968
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021590 ENSBTAP00000021590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007275 multicellular organismal development
GO:0032502 developmental process
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000118004
View Gene Order
ENSMUSG00000036655
View Gene Order
Pathways
NETPATH
REACTOME
REACT_209041
Scavenging by Class A Receptors pathway
REACT_213817
Binding and Uptake of Ligands by Scavenger Receptors pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160300
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_163699
Scavenging by Class A Receptors pathway
REACT_196573
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_196581
Scavenging by Class A Receptors pathway
KEGG
hsa04145
Phagosome pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt Q17QH6
TrEMBL
UniProt Splice Variant
Entrez Gene 613991
UniGene Bt.20999
RefSeq NM_001076303 XM_005210613 XM_005210614
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118358
GenPept AAI18359
RNA Seq Atlas 613991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca