Version 5.4
Bos taurus Protein: COLEC11
Summary
InnateDB Protein IDBP-691100.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COLEC11
Protein Name Collectin-11
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021590
InnateDB Gene IDBG-638985 (COLEC11)
Protein Structure
UniProt Annotation
Function Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N- acetylgalactosamine. Binds to lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007275 multicellular organismal development
GO:0032502 developmental process
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR008160 Collagen triple helix repeat
IPR016187 C-type lectin fold
PFAM PF00059
PF01391
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q17QH6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 613991
UniGene Bt.20999
RefSeq NP_001069771
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118358
GenPept AAI18359

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca