Bos taurus Gene: TMSB4
Summary
InnateDB Gene IDBG-639164.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMSB4
Gene Name thymosin beta-4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000038488
Encoded Proteins
Thymosin beta-4Hematopoietic system regulatory peptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205542:
This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:140973702-140975767
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024387 ENSBTAP00000024387
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0030036 actin cytoskeleton organization
GO:0030334 regulation of cell migration
GO:0042989 sequestering of actin monomers
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Platelet activation, signaling and aggregation pathway
Hemostasis pathway
Platelet degranulation pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Response to elevated platelet cytosolic Ca2+ pathway
KEGG
Regulation of actin cytoskeleton pathway
Regulation of actin cytoskeleton pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C1K3N7 G8JKY5
UniProt Splice Variant
Entrez Gene 785745
UniGene Bt.102615 Bt.65336 Bt.75045 Bt.8122
RefSeq NM_001113231 XM_002706880 XM_005193186 XM_005194518 XM_005194621 XM_005196273 XM_005215562 XM_005222037
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY911377 BC133478 DAAA02075466 FJ795030
GenPept AAI33479 AAW82140 ACO37642
RNA Seq Atlas 100137883 101906407 101906455 101906565 101909582 282386 781334 785745