Version 5.4
Bos taurus Gene: MAPK3
Summary
InnateDB Gene IDBG-639178.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAPK3
Gene Name mitogen-activated protein kinase 3
Synonyms ERK1
Species Bos taurus
Ensembl Gene ENSBTAG00000016156
Encoded Proteins
IDBP-691317
mitogen-activated protein kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 25:26437044-26444129
Strand Forward strand
Band
Transcripts
ENSBTAT00000021507 ENSBTAP00000021507
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0001784 phosphotyrosine binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019902 phosphatase binding
Biological Process
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0006351 transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0006975 DNA damage induced protein phosphorylation
GO:0009887 organ morphogenesis
GO:0016310 phosphorylation
GO:0019233 sensory perception of pain
GO:0030509 BMP signaling pathway
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0033129 positive regulation of histone phosphorylation
GO:0035066 positive regulation of histone acetylation
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0043330 response to exogenous dsRNA
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 cartilage development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070849 response to epidermal growth factor
GO:0071260 cellular response to mechanical stimulus
GO:2000657 negative regulation of apolipoprotein binding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0015630 microtubule cytoskeleton
GO:0031143 pseudopodium
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.5687
RefSeq NM_001110018 XM_005224919
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca