Bos taurus Gene: ALDOA | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||
InnateDB Gene | IDBG-639227.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | ALDOA | ||||||||||||||||
Gene Name | fructose-bisphosphate aldolase A | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000012927 | ||||||||||||||||
Encoded Proteins |
fructose-bisphosphate aldolase C-A
|
||||||||||||||||
Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149925:
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011] |
||||||||||||||||
Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 25:26470488-26475202 | ||||||||||||||||
Strand | Reverse strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
|
||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
|
||||||||||||||||
Gene Ontology | |||||||||||||||||
Molecular Function |
|
||||||||||||||||
Biological Process |
|
||||||||||||||||
Cellular Component |
|
||||||||||||||||
Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH |
EGFR1 pathway
|
||||||||||||||||
REACTOME |
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Glycolysis pathway
Gluconeogenesis pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Platelet activation, signaling and aggregation pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
Hemostasis pathway
Platelet degranulation pathway
Disease pathway
Hemostasis pathway
Glycolysis pathway
Glucose metabolism pathway
Metabolism pathway
Platelet activation, signaling and aggregation pathway
Gluconeogenesis pathway
Glycogen storage diseases pathway
Response to elevated platelet cytosolic Ca2+ pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
|
||||||||||||||||
KEGG |
Glycolysis / Gluconeogenesis pathway
Pentose phosphate pathway pathway
Fructose and mannose metabolism pathway
Pentose phosphate pathway pathway
Fructose and mannose metabolism pathway
Glycolysis / Gluconeogenesis pathway
|
||||||||||||||||
INOH |
Glycolysis Gluconeogenesis pathway
Fructose Mannose metabolism pathway
Pentose phosphate cycle pathway
|
||||||||||||||||
PID NCI |
HIF-1-alpha transcription factor network
|
||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | A6QLL8 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 509566 | ||||||||||||||||
UniGene | Bt.22533 | ||||||||||||||||
RefSeq | NM_001101915 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | BC148010 DAAA02057895 | ||||||||||||||||
GenPept | AAI48011 | ||||||||||||||||
RNA Seq Atlas | 509566 | ||||||||||||||||